Last update July 31, 2016

Ceftazidime

Compatible

Safe substance and/or breastfeeding is the best option.

Tiny amount of Cephalosporin is excreted into human milk.

Be aware of false negative bacterial cultures in the infant when the mother is on antibiotics.

American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.
Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

Alternatives

We do not have alternatives for Ceftazidime since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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José María Paricio, founder of e-lactancia.
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Other names

Ceftazidime in other languages or writings:

Group

Ceftazidime belongs to this group or family:

Tradenames

Main tradenames from several countries containing Ceftazidime in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. < 10 %
Molecular weight 637 daltons
Protein Binding 10 %
VD 0.23 l/Kg
Tmax 1 - 1.5 hours
T½ 1.5 - 2 hours
Theoretical Dose 0.8 mg/Kg/d
Relative Dose 1 - 5 %
Ped.Relat.Dose 0.8 %

References

  1. van Wattum JJ, Leferink TM, Wilffert B, Ter Horst PGJ. Antibiotics and lactation: An overview of relative infant doses and a systematic assessment of clinical studies. Basic Clin Pharmacol Toxicol. 2019 Jan;124(1):5-17. Abstract
  2. Rowe H, Baker T, Hale TW. Maternal medication, drug use, and breastfeeding. Pediatr Clin North Am. 2013 Feb;60(1):275-94. Abstract
  3. AEMPS. Ceftazidima. Ficha técnica. 2012 Full text (in our servers)
  4. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Abstract Full text (link to original source) Full text (in our servers)
  5. AAP - American Academy of Pediatrics Committee on Drugs. Transfer of drugs and other chemicals into human milk. Pediatrics. 2001 Sep;108(3):776-89. Abstract Full text (link to original source) Full text (in our servers)
  6. Fulton B, Moore LL. Antiinfectives in breastmilk. Part I: Penicillins and cephalosporins. J Hum Lact. 1992 Abstract
  7. Blanco JD, Jorgensen JH, Castaneda YS, Crawford SA. Ceftazidime levels in human breast milk. Antimicrob Agents Chemother. 1983 Abstract Full text (link to original source) Full text (in our servers)

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America

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