Last update Oct. 15, 2016
Very Low Risk
Third generation cephalosporins for oral administration.
At latest update no published data on excretion into breast milk were found.
Most cephalosporins are excreted into milk in insignificant amounts from a therapeutic point of view without reported complications in infants.
Cephalosporins are widely used in the Pediatric practice with a good tolerance, even in the neonatal period, so it is very unlikely that in small amounts through milk would be a cause of problems in the infant.
Pharmacokinetic data (moderately high molecular weight, high protein binding capacity and short half-life span) make unlikely the milk passage of significant amounts into breast milk.
Their low oral bioavailability hinders the passage from ingested milk to the infant’s plasma except in preterm babies and immediate neonatal period, when they may exhibit an increased intestinal permeability.
Be aware of the possibility of false negative results of cultures in febrile infants whose mothers are taking antibiotics as well as the possibility of gastroenteritis (Ito 1993) by altering the intestinal flora.
We do not have alternatives for Cefditoren Pivoxil since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM