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Second-generation cephalosporin antibiotic for injection or parenteral administration.
At latest update no published data on excretion into breast milk were found.
Pharmacokinetic data (short half-life span) make unlikely the milk passage of significant amounts into breast milk.
Their low oral bioavailability hinders the passage from ingested milk to the infant’s plasma except in preterm babies and immediate neonatal period, when they may exhibit an increased intestinal permeability.
Most cephalosporins are excreted into milk in insignificant amounts from a therapeutic point of view (Rowe 2013, Fulton 1992) without reported complications in infants.
Cephalosporins are widely used in the Pediatric practice with a good tolerance, even in the neonatal period, so it is very unlikely that in small amounts through milk would be a cause of problems in the infant.
Although rare, the possibility of transient gastroenteritis due to alteration of the intestinal microbiome in infants whose mothers take antibiotics should be taken into account. (Ito 1993)
Expert authors consider cephalosporins safe for use during breastfeeding. (Bar 2003)