Last update July 10, 2017
Limited compatibility
We do not have alternatives for C9H8ClN5S.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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C9H8ClN5S is Tizanidine Hydrochloride in Molecular formula.
Is written in other languages:Main tradenames from several countries containing C9H8ClN5S in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 40 | % |
Molecular weight | 290 | daltons |
Protein Binding | 30 | % |
VD | 2.6 | l/Kg |
Tmax | 1 | hours |
T½ | 2 - 4 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Centrally acting muscle relaxant.
Since the last update we have not found published data on its excretion in breast milk.
Its pharmacokinetic data: low molecular weight, high liposolubility (Acorda 2006), makes it probable that it could pass to milk in potentially significant quantities.
During breastfeeding, it seems prudent to avoid it (Hutchinson 2013) or to use it very sporadically and limited to sufficient minimum doses, monitoring for possible sedation of the infant, especially during the first 3 months of life.