Last update Nov. 16, 2019
Relaxant drug of the muscle with action on the Central Nervous System and chemically related to tricyclic antidepressants.
Indicated in muscle spasms of musculoskeletal origin.
Oral administration one to three times a day, maximum 2 weeks.
Its pharmacokinetic data (large volume of distribution and high percentage of protein binding) explain the very small passage to milk observed (Burra 2019).
No problems have been observed in two infants whose mothers took it for months since birth (Burra 2019).
A 16-day-old newborn whose mother took cyclobenzaprine, paracetamol and oxycodone had recoverable cardiorespiratory problems (Beauchamp 2019).
It is recommended to use the lowest effective dose possible.
Long-term treatments or those mothers who are nursing a newborn or premature infant would be prudent the use of a known safer alternative or with a shorter elimination half life.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM