Last update Dec. 30, 2021
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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C21H25ClN2O3 is Levocetirizine in Molecular formula.
Is written in other languages:C21H25ClN2O3 is also known as
Main tradenames from several countries containing C21H25ClN2O3 in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 100 | % |
Molecular weight | 389 | daltons |
Protein Binding | 92 | % |
VD | 0.4 | l/Kg |
Tmax | 1 | hours |
T½ | 8 - 12 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Second generation antihistamine, derived from piperazine, with minimal sedative effects and very low toxicity even at high doses.
Since the last update we have not found published data on its excretion in breast milk, but it is an enantiomer and active metabolite of cetirizine, that It is excreted in breast milk in clinically insignificant amounts (Wilkerson 2021). No problems were detected in the short or long term in an infant whose mother took cetirizine during the first month after delivery as part of the treatment for pemphigus.(Westermann 2012)
Its high binding to plasma proteins makes its transfer to milk unlikely.
The British Society for Allergy and Clinical Immunology considers cetirizine safe during breastfeeding. (Powell 2007)
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