Last update April 25, 2022
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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C10H16N6S is Cimetidine in Molecular formula.
Is written in other languages:C10H16N6S is also known as
C10H16N6S belongs to this group or family:
Main tradenames from several countries containing C10H16N6S in its composition:
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
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Cimetidine is a histamine H2 antagonist that inhibits gastric acid secretion and pepsin production. It is used in peptic ulcer disease and gastroesophageal reflux. Oral or parenteral administration one to four times daily.
It is excreted in breast milk in moderate amount (Oo 1995, Somogyi 1979), though lower than the dose used in newborns and infants (5 - 10 mg/kg/day). (Rowe 2013)
Several medical societies, experts and expert consensus, consider the use of this medication to be safe or very probably safe during breastfeeding. (Hale 2019, Briggs 2017, Rowe 2013, Mahadevan 2006, Richter 2005, Nice 2000, Lee 1993)
American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable (Rowe 2013, WHO 2002, Nice 2000. Lee 1992), especially during the neonatal period and in the event of prematurity.
Famotidine and Nizatidine are excreted into milk but in less proportion than Cimetidine or Ranitidine, which have been proposed as alternative to during lactation. (Schaefer 2015, Rowe 2013, Nice 2000, Hagemann 1998, Lee 1993)