Last update May 21, 2021

Bromides

Limited compatibility

Unsafe. Moderate/severe adverse effects. Compatible under certain circumstances. Follow-up recommended. Use safer alternative or discontinue breastfeeding from 5 to 7 T ½ . Read Commentary.

Certain bromide oxides or salts have central nervous system depressant properties and have been used, especially potassium bromide, as sedatives and antiepileptics until well into the 20th century. Along with other compounds, they also appear in cough preparations.
They have been replaced by safer and more effective drugs and their marketing has been suspended in most countries of the world and relegated to veterinary use.
They are also used in the photography industry.

They are excreted in human milk in amounts that may be significant, and rashes, weakness, hypotonia and drowsiness have been observed in infants whose mothers took this medication (Reisner 1983, Van der Bogert 1921: in Hale 2021).

Known safer alternatives during lactation are preferable, especially during the neonatal period and in the case of prematurity.


See below the information of this related product:

  • Bromum (Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.)

Alternatives

  • Diazepam (Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.)
  • Phenobarbital (Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.)
  • Zaleplon (Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Bromides is also known as


Bromides in other languages or writings:

Group

Bromides belongs to this group or family:

Tradenames

Main tradenames from several countries containing Bromides in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 97 - 119 daltons
288 hours

References

  1. Reisner SH, Eisenberg NH, Stahl B, Hauser GJ. Maternal medications and breast-feeding. Dev Pharmacol Ther. 1983;6(5):285-304. Review. Abstract
  2. Van der Bogert F. Bromine poisoning through mother's milk. Am J Dis Child 1921; 21:167. In: Hale TW. Hale's Medications & Mothers' Milk. Springer Publishing Company. 2021

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