Last update May 4, 2022
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Bismuth Salicylate is also known as
Bismuth Salicylate in other languages or writings:
Bismuth Salicylate belongs to these groups or families:
Main tradenames from several countries containing Bismuth Salicylate in its composition:
|Oral Bioavail.||Bi: < 1 - Salic: 80||%|
|Protein Binding||Bi: 90 - Salic: 70 - 95||%|
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e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Bismuth salicylate contains about 60% bismuth and 40% salicylate. It is used against gastritis and diarrhea. Oral administration
At latest update no published data on excretion into breast milk were found.
A very small amount of bismuth is absorbed from the gut: ≈ 0.1% (Tora 2020, Chen 2010, Boertz 2009, Dresow 1992, Nwokolo 1990: Bismuth is not absorbed into the systemic circulation of the mother, so it cannot be excreted in breast milk.
Salicylate is well absorbed (Nwokolo 1990), but is excreted in breast milk in negligible amounts, and the infant receives a relative dose of 1% (see Aspirin) and no cases of Reye's syndrome have been reported after taking bismuth salicylate or other non-acetylated salicylate compounds.
Due to the otherwise minimum risk of Reye's syndrome and the indiscriminate use of bismuth subsalicylate for treatment of gastroenteritis cannot be justifiable since most of gastroenteritis do not require medication instead a simply adequate hydration, a safer alternative should be desirable while breastfeeding. (Chen 2010, Nice 2000)
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