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Intestinal stimulant laxative used in the treatment of constipation and for bowel evacuation prior to investigative procedures or surgery. Oral or rectal administration.
Its very low oral bioavailability due to minimal intestinal absorption results in very low plasma levels, which explains the absence of transfer to breast milk (undetectable levels). (Friedrich 2011)
Expert authors consider the use of this medication during breastfeeding to be acceptable. (Hale, LactMed, Gharehbaghi 2016)
On prevention or treating constipation, it is essential a balanced and rich-in-fiber diet along with a lot of fluids and physical exercise.