Last update Jan. 25, 2022

Βουτριπτυλλίνη υδροχλωρική

High Risk

Poorly safe. Evaluate carefully. Use safer alternative or interrupt breastfeeding 3 to 7 T ½ (elimination half-lives). Read the Comment.

Tricyclic antidepressant derivative of amitriptyline with actions and uses similar to those of amitriptyline. It has marked antimuscarinic and sedative properties. Used in the treatment of depression.

Product with very few bibliographical references and that has been withdrawn from the market worldwide.

Alternatives

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Βουτριπτυλλίνη υδροχλωρική is Butriptyline Hydrochloride in Greek.

Is written in other languages:

Group

Βουτριπτυλλίνη υδροχλωρική belongs to this group or family:

Tradenames

Main tradenames from several countries containing Βουτριπτυλλίνη υδροχλωρική in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 330 daltons
Protein Binding 90 %
Tmax 2.6 - 7.5 hours
20 hours

References

  1. Remakus BL, Kessel LJ, Trichtinger MD, Montgomery P, Griffiths JP. Butriptyline (Evadyne) and the Mexican connection. N Engl J Med. 1981 Jun 18;304(25):1543-4. No abstract available. Abstract
  2. Bourgouin J, Gagnon MA, Elie R, Dvornik D, Gonzalez R, Kraml M. Butriptyline: human pharmacokinetics and comparative bioavailability of conventional and sustained release formulations. Biopharm Drug Dispos. 1981 Apr-Jun;2(2):123-30. Abstract

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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America

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