Last update Oct. 25, 2023
Compatible
We do not have alternatives for アルカフタジン since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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アルカフタジン is Alcaftadine in Japanese.
Is written in other languages:アルカフタジン belongs to this group or family:
Variable | Value | Unit |
---|---|---|
Molecular weight | 307 | daltons |
Protein Binding | 39 - 63 | % |
Tmax | 0.25 | hours |
T½ | 2 | hours |
Theoretical Dose | < 0.00001 | mg/Kg/d |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by IHAN of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Alcaftadine is a histamine H1-receptor antagonist for ophthalmic use to prevent itching associated with allergic conjunctivitis in adults and children from 2 years of age. Topical administration once daily as eye drops.
At the time of the last update, we found no published data on its excretion in breast milk.
It reaches peak plasma concentrations of less than 120 pg/ml (Bohets 2011, Allergan 2011), so passage into milk must be negligible.
The small dose and low plasma absorption of most topical ophthalmic preparations make passage of significant amounts into breast milk unlikely.
For ophthalmic administration, absorption can be minimised by pressing the tear duct (inner canthus of the eye) with the finger for 1-2 minutes and administering the dose immediately after breastfeeding. (Belkin 2020, Blumen 2020)