Last update Dec. 19, 2013

Alcaftadine

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Topical ophthalmologic anti-histaminic drug that achieves very low plasma concentration with only 60 pg/mL. Hence, an insignificant excretion into breast milk should be advanced.

Alternatives

We do not have alternatives for Alcaftadine since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Group

Alcaftadine belongs to this group or family:

Tradenames

Main tradenames from several countries containing Alcaftadine in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 307 daltons
Protein Binding 39 - 63 %
Tmax 0.25 hours
T½ 2 hours
Theoretical Dose < 0.00001 mg/Kg/d

References

  1. Bohets H, McGowan C, Mannens G, Schroeder N, Edwards-Swanson K, Shapiro A. Clinical pharmacology of alcaftadine, a novel antihistamine for the prevention of allergic conjunctivitis. J Ocul Pharmacol Ther. 2011 Abstract
  2. Alcaftadina. Ficha técnica. 2011 Full text (in our servers)
  3. Alcaftadine. Data Sheet. 2011 Full text (in our servers)

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