Last update Nov. 7, 2024

Arformoterol Tartrate

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

El arformoterol es el enantiómero R,R del agonista del receptor beta2-adrenérgico formoterol. Es un broncodilatador beta-2 adrenérgico selectivo de acción prolonfgada similar al salmeterol. Al igual que el salbutamol, es de características similares a la Terbutalina. Administracion inhalada.

A fecha de la última actualización no encontramos datos publicados sobre su excreción en leche materna.

La absorcion por inhalacion es mínima y los niveles plasmaticos muy bajos.

Su relativamente elevado peso molecular hace improbable su paso a leche.

Diversas sociedades médicas y autores expertos consideran seguro el uso de broncodilatadores inhalados durante la lactancia debido a los bajos niveles séricos maternos. (Hale, Lactmed, Bendien 2024, Amir 2011, National Asthma 2004, Nelson 2001, Ellsworth 1994)

Alternatives

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Arformoterol Tartrate in other languages or writings:

Group

Arformoterol Tartrate belongs to this group or family:

Tradenames

Main tradenames from several countries containing Arformoterol Tartrate in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 495 daltons
Protein Binding 52 - 65 %
pKa 8.61 -
Tmax 0.5 - 3 hours
26 hours

References

  1. Bendien SA, de Kruif MD, Feitsma H, van Hoolwerff-Blikkendaal C, Huurne KK, Kuiterman A, Baranova EV, Wittkamp A, Brons A, Poulissen M, van der Meer AN. Summary of the Dutch Multidisciplinary Practice Guideline on Asthma and Pregnancy. J Allergy Clin Immunol Pract. 2024 Jul;12(7):1751-1762. Consulted on Nov. 7, 2024 Abstract
  2. LactMed. Drugs and Lactation Database (LactMed). Internet. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/ 2006 - Consulted on April 16, 2024 Full text (link to original source)
  3. Hale TW. Medications & Mothers' Milk. 1991- . Springer Publishing Company. Available from https://www.halesmeds.com Consulted on April 10, 2024 Full text (link to original source)
  4. Sunovion Pharmaceuticals Inc Arformoterol Data Sheet 2012 Full text (in our servers)
  5. National Asthma Education and Prevention Program Asthma and Pregnancy Working Group. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. 2004;1-57. None 2004 Full text (link to original source) Full text (in our servers)
  6. Nelson-Piercy C. Asthma in pregnancy. Thorax. 2001 Abstract Full text (link to original source) Full text (in our servers)
  7. Ellsworth A. Pharmacotherapy of asthma while breastfeeding. J Hum Lact. 1994 Abstract

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