Last update Nov. 7, 2024
Compatible
We do not have alternatives for Salmeterol Xinafoate since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Salmeterol Xinafoate in other languages or writings:
Salmeterol Xinafoate belongs to this group or family:
Main tradenames from several countries containing Salmeterol Xinafoate in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 100 | % |
Molecular weight | 604 | daltons |
Protein Binding | 96 - 98 | % |
VD | 2.5 - 45.1 | l/Kg |
pKa | 10.12 | - |
Tmax | 0.1 - 0.3 | hours |
T½ | 5.5 | hours |
M/P ratio | 1 | - |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Long-acting bronchodilator similar in structure to salbutamol. Inhaled twice daily administration.
At the date of last update we did not find published data on its excretion in breast milk.
Its high binding to plasma proteins, very large volume of distribution, moderately high molecular weight and the fact that, after inhalation, it reaches very low or undetectable plasma concentrations (Hale, Cazzola 2002, AEMPS 2012) make it very unlikely that significant quantities will pass into milk.
Terbutaline, a molecule of the same family, is excreted in negligible amounts in breast milk.
Several medical societies and expert authors consider the use of inhaled bronchodilators safe during breastfeeding due to low maternal serum levels (Lactmed, Bendien 2024, Amir 2011, National Asthma 2004, Nelson 2001, Ellsworth 1994).
See below the information of this related product: