Last update Sept. 5, 2022
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Amantadine Hydrochloride is also known as
Amantadine Hydrochloride in other languages or writings:
Amantadine Hydrochloride belongs to these groups or families:
Main tradenames from several countries containing Amantadine Hydrochloride in its composition:
|Oral Bioavail.||86 - 90||%|
|VD||4.2 (3 - 8)||l/Kg|
|Tmax||1 - 4||hours|
|T½||10 - 15||hours|
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e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a dopamine agonist that is used as an antiparkinsonian. It also has antiviral properties and is used in the treatment and prophylaxis of influenza type A and herpes zoster. Oral administration.
At latest update relevant published data on excretion into breast milk were not found. Because of large volume of distribution and low plasma level observed (Pacifici 1976), a passage of significant amount through breastmilk or side-effects on the infant are not likely to occur.
Amantadine reduces plasma levels of prolactin, it has been used to treat galactorrhea caused by the use of dopaminergic neuroleptic drugs (Siever 1981 Correa 1987, Marken 1992, Carvalho 2011), however there is not information about the effect on lactating mothers. Prolactin is important to milk production especially during the first few weeks within birth. Frequent and effective stimulation of the nipple by the infant is essential on the maintenance of breastfeeding.
Whether administered during breastfeeding, it would be advisable not to use it in the neonatal period and monitor milk production.