Last update: Dec. 8, 2017

Vardenafil

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

A 5-phosphodiesterase inhibitor with uses similar to sildenafil, used in the treatment of pulmonary hypertension, erectile dysfunction in men, Raynaud's syndrome and in other treatments due to its vasodilatory effect on smooth muscle.

Since the last update, we have not found published data on its excretion in breast milk.

Its high percentage of protein binding makes it unlikely that it will be transferred to milk in significant amounts, as in fact has been seen in another drug from the same therapeutic group, sildenafil.

Until there is more published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in case of prematurity.

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Vardenafil is also known as


Vardenafil in other languages or writings:

Tradenames

Main tradenames from several countries containing Vardenafil in its composition:

Pharmacokinetics

Variable Value Unit
Bioavailability 15 %
Molecular weight 489 daltons
Protein Binding 95 %
VD 2,9 l/Kg
Tmax 1 (0,5 - 2) hours
T1/2 4 - 5 hours

References

  1. EMA. Vardenafil. Drug Summary. 2017 Full text (in our servers)
  2. EMA. Vardenafilo. Ficha técnica. 2017 Full text (in our servers)

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