Last update: July 11, 2016

Syncaine

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

At latest update no published data on excretion into breast milk was found.

Topical anesthetics (dermatological and mouth preparations when correctly applied like creams, subcutaneous injections for infiltration or spinal anesthesia) have negligible systemic absorption.
Pharmacokinetic data (poor absorption and short half-life span) make it highly unlikely the passage into milk in significant amount.

Do not apply it on the chest or, whenever necessary, apply it after having nursed the baby and clean it thoroughly up with water before the next meal.

Having been published less experience than with other drugs of the same group, it would be preferable the use of a known safer alternative, especially during the neonatal period and in case of premature birth.

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Syncaine is also known as Procaine Hydrochloride. Here it is a list of alternative known names::


Syncaine in other languages or writings:

Group

Syncaine belongs to this group or family:

Tradenames

Main tradenames from several countries containing Syncaine in its composition:

Pharmacokinetics

Variable Value Unit
Bioavailability Baja - Poor %
Molecular weight 273 daltons
Protein Binding 6 %
T1/2 0,1 hours

References

  1. AEMPS. Procaína. Ficha técnica. 2007 Full text (in our servers)
  2. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)

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