Last update: Aug. 22, 2019
Not risky for breastfeeding or infant.
Amide-type local anesthetic, usually associated with epinephrine, used in dental, local and regional anesthesia (infiltration and epidural).
Since the last update we have not found published data in relation to breastfeeding.
It is immediately hydrolyzed to inactive articainic acid (van Oss 1989 and 1988), so no systemic toxicity is observed (AEMPS 2019, FDA 2006), even after unintentional systemic injection (Oertel 1997).
In addition, its short elimination half-life and wide distribution volume would prevent excretion in breastmilk in significant quantities.
According to the manufacturer, it is not necessary to stop breastfeeding since there are no clinically relevant levels in breastmilk (AEMPS 2019).
If ingested orally, it is rapidly hydrolyzed by gastric esterases, which would prevent it from reaching the infant's plasma from breastmilk (Hale 2019).
Due to its characteristics, it is the local anesthetic of choice during breastfeeding for dental and infiltration procedures (Nizharadze 2011).
We do not have alternatives for Articaine Hydrochloride since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM