Last update: Oct. 28, 2014
Safe. Compatible.
Not risky for breastfeeding or infant.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
St. John´s Wort is also known as
St. John´s Wort belongs to these groups or families:
Main tradenames from several countries containing St. John´s Wort in its composition:
Variable | Value | Unit |
---|---|---|
Molecular weight | 504 | daltons |
Tmax | 2 - 2,6 | hours |
T1/2 | 24,8 - 26,5 | hours |
Theoretical Dose | 0,00009 | mg/Kg/d |
Relative Dose | < 1 | % |
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e-lactancia is a resource recommended by AELAMA
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Herb commonly used from ancient times. Firm evidence is available on its effectiveness for treatment of depression, to the extent that it should be avoided a sudden stop of medication to prevent a rebound effect.
It has been also topically used for the treatment of wounds, burns and eczema due to healing and antiseptical properties.
Constituents are: Hypericin, Hyperforin and Quercetin. Antidepressant properties are attributed to Hypericin but mostly to Hyperforin. Quercetin is a flavonoid which is commonly found in many fruits and eatable vegetables.
Hyperforin is excreted into breast milk in nil or clinically non-significant amount with not side-effects reported among breastfed infants from treated mothers, except for isolated and dubious cases of somnolence and colicky pain with spontaneous resolution with no medical intervention being required. Plasma levels in those infants were undetectable or close to the lower detectable point (0.1μg/L).
Hypericin has not been detected in the breast milk. Quercetin levels found were as low as of few nanomols/L., and related to composition of fruits and vegetables of diet.
It is most important to make sure that composition and amount of Hypericum contained in commercially available products is correct, do not take it without medical surveillance, avoid sudden stop and consider pharmacological interactions with many other medications.