Last update: Dec. 15, 2018
Minimal risk for breastfeeding and infant.
Tricyclic antidepressant, active metabolite of amitriptyline. Oral administration 3 to 4 times a day
Excreted into breast milk in a clinically non-significant amount (Wisner 1997,Matheson 1988, Brixen1982) with no problems observed in breastfed infants from treated mothers (Wisner 2002, 1997 y 1991,Brixen1982).
Levels found in the plasma of those infants were very low or undetectable Wisner 2006 y 1991).
It is considered one of the safest antidepressants during lactation (Gentile 2014, Nielsen 2012, Hübner 2012, Pringsheim 2012, Davanzo 2011, Lanza 2009, ABM 2008, Weissman 2004).
We do not have alternatives for Nortriptyline Hydrochloride since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Instituto de Salud Infantil, Grecia-Institute of Child's Health in Greece
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM