Last update: July 31, 2018
Not risky for breastfeeding or infant.
A strong opioid analgesic equivalent to morphine with a partially antagonistic action.
It is used during childbirth and cesarean section.
Administered subcutaneously, intramuscularly or intravenously every 3 to 6 hours.
There is a dosage and it is considered safe in the pediatric age group without causing respiratory depression (Kubica-Cielińska 2015).
Unlike other opioids, its metabolites are inactive (Martin 2018).
It is excreted in breastmilk in clinically insignificant amounts (Reece 2017, Mustafa 2016, FDA 2016, Jacqz-Aigrain 2007, Wischnik 1988).
Its low oral bioavailability (Aitkenhead 1988) hinders transfer to the infant’s plasma from ingested breastmilk.
It can increase the secretion of prolactin (Saarialho 1988).
Not available in several countries including Spain.
We do not have alternatives for Nalbuphine Hydrochloride since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM