Last update: April 8, 2014

Modafinil

High Risk for breastfeeding


Poorly safe. Evaluate carefully.
Use safer alternative or interrupt breastfeeding several T½.
Read the Comment.

Used for treatment of narcolepsy.

On latest update relevant data on breastfeeding was not found.

Pharmacokinetic data indicates that drug excretion into breast milk would be significant.

Until more information concerning breastfeeding is available, a safer alternative is preferred.

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Modafinil is also known as


Group

Modafinil belongs to this group or family:

Tradenames

Main tradenames from several countries containing Modafinil in its composition:

Pharmacokinetics

Variable Value Unit
Bioavailability 100 %
Molecular weight 273 daltons
Protein Binding 60 %
VD 0,9 l/Kg
Tmax 2 - 4 hours
T1/2 15 hours

References

  1. Hoque R, Chesson AL Jr. Conception, pregnancy, delivery, and breastfeeding in a narcoleptic patient with cataplexy. J Clin Sleep Med. 2008 Abstract Full text (link to original source) Full text (in our servers)
  2. Wise MS, Arand DL, Auger RR, Brooks SN, Watson NF; American Academy of Sleep Medicine. Treatment of narcolepsy and other hypersomnias of central origin. Sleep. 2007 Abstract Full text (link to original source) Full text (in our servers)

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