Last update: June 30, 2015

Armodafinil

High Risk for breastfeeding


Poorly safe. Evaluate carefully.
Use safer alternative or interrupt breastfeeding several T½.
Read the Comment.

Used for treatment of narcolepsy.

On latest update relevant data on breastfeeding was not found.

Pharmacokinetic data indicates that drug excretion into breast milk would be significant.

Until more information concerning breastfeeding is available, a safer alternative is preferred.

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Armodafinil in other languages or writings:

Group

Armodafinil belongs to this group or family:

Tradenames

Main tradenames from several countries containing Armodafinil in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 273 daltons
Protein Binding 60 %
VD 0,6 l/Kg
Tmax 2 - 4 hours
T1/2 15 hours

References

  1. Calvo-Ferrandiz E, Peraita-Adrados R. Narcolepsy with cataplexy and pregnancy: a case-control study. J Sleep Res. 2018 Abstract
  2. Armodafinilo Ficha técnica 2010 Full text (in our servers)
  3. Armodafinil Data Sheet 2010 Full text (in our servers)
  4. Hoque R, Chesson AL Jr. Conception, pregnancy, delivery, and breastfeeding in a narcoleptic patient with cataplexy. J Clin Sleep Med. 2008 Abstract Full text (link to original source) Full text (in our servers)
  5. Spigset O, Brede WR, Zahlsen K. Excretion of methylphenidate in breast milk. Am J Psychiatry. 2007 Abstract Full text (link to original source) Full text (in our servers)
  6. Wise MS, Arand DL, Auger RR, Brooks SN, Watson NF; American Academy of Sleep Medicine. Treatment of narcolepsy and other hypersomnias of central origin. Sleep. 2007 Abstract Full text (link to original source) Full text (in our servers)
  7. Heikkinen T, Ekblad U, Palo P, Laine K. Pharmacokinetics of fluoxetine and norfluoxetine in pregnancy and lactation. Clin Pharmacol Ther. 2003 Abstract

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