Last update: June 4, 2016

Lercanidipine Hydrochloride

Low Risk for breastfeeding

Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

At latest update no published data were found on excretion into breast milk.

Evidence on other antihypertensive drugs of the same family with similar structure, pharmacokinetics and action profile (nifedipine, nimodipine, nicardipine) has shown that they are excreted into milk in non-significant amount.
Its high plasma protein binding capacity makes it unlikely any passage to the milk, however, its high lipid solubility facilitates excretion into it.

Although it has a low oral bioavailability, it may increase to four times if administered with a fatty meal, which would increase the oral absorption in the infant.

Until more extensive published data about this drug regarding breastfeeding are available a safer alternative drug should be used, especially during the neonatal period and/or in case of premature infants.


Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Lercanidipine Hydrochloride is also known as

Lercanidipine Hydrochloride in other languages or writings:


Lercanidipine Hydrochloride belongs to this group or family:


Main tradenames from several countries containing Lercanidipine Hydrochloride in its composition:


Variable Value Unit
Oral Bioavail. 10 %
Molecular weight 648 daltons
Protein Binding 98 %
Tmax 1,5 - 3 hours
T1/2 8 - 10 hours


  1. ARTG. Lercanidipine. Product Monograph. 2014 Full text (in our servers)
  2. AEMPS. Lercanidipino. Ficha técnica. 2011 Full text (in our servers)

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