Last update: Nov. 14, 2014

Isometheptene

High Risk for breastfeeding


Poorly safe. Evaluate carefully.
Use safer alternative or interrupt breastfeeding 3 to 7 T½.
Read the Comment.

Seemingly a sympathomimetic drug with poor effect on Migraine relief.

On latest update relevant data on breastfeeding was not found.

Because a low excretion into breast milk Sumatriptan is a preferred drug.

Other medication for Migraine relief like Triptans, Ibuprofen, Diclofenac and Ketorolate are more effective and at a lower risk for breastfeeding than Isometheptene.

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Group

Isometheptene belongs to this group or family:

Tradenames

Main tradenames from several countries containing Isometheptene in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 493 daltons

References

  1. Duong S, Bozzo P, Nordeng H, Einarson A. Safety of triptans for migraine headaches during pregnancy and breastfeeding. Can Fam Physician. 2010 Abstract Full text (link to original source) Full text (in our servers)
  2. Jürgens TP, Schaefer C, May A. Treatment of cluster headache in pregnancy and lactation. Cephalalgia. 2009 Abstract
  3. Marcus DA. Managing headache during pregnancy and lactation. Expert Rev Neurother. 2008 Abstract
  4. Raña-Martínez N. Migraña en la mujer. [Migraine in females]. Rev Neurol. 2008 Abstract
  5. Beseler-Soto B, Paricio-Talayero JM, Sánchez-Palomares M, Benlloch-Muncharaz M, Santos-Serrano L, Landa-Rivera L. MIgraña en la mujer. [Migraine and female]. Rev Neurol. 2008 Abstract
  6. MacGregor EA. Migraine in pregnancy and lactation: a clinical review. J Fam Plann Reprod Health Care. 2007 Abstract Full text (in our servers)
  7. Loder E. Migraine in pregnancy. Semin Neurol. 2007 Abstract
  8. Sances G, Granella F, Nappi RE, Fignon A, Ghiotto N, Polatti F, Nappi G. Course of migraine during pregnancy and postpartum: a prospective study. Cephalalgia. 2003 Abstract
  9. Allais G, Bosio A, Mana O, Airola G, Ciochetto D, Terzi MG, De Lorenzo C, Quirico PE, Benedetto C. [Migraine during pregnancy and lactation: treatment of the acute attack and non-pharmacological prophylactic strategies]. Minerva Med. 2003 Abstract
  10. Wojnar-Horton RE, Hackett LP, Yapp P, Dusci LJ, Paech M, Ilett KF. Distribution and excretion of sumatriptan in human milk. Br J Clin Pharmacol. 1996 Abstract Full text (link to original source) Full text (in our servers)

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