Last update: April 16, 2015

Flufenamic Acid

Very Low Risk for breastfeeding

Safe. Compatible.
Minimal risk for breastfeeding and infant.

It is a non-steroidal anti-inflammatory topically used which is chemically related to Mefenamic acid. There are also formulations for oral use.

Excreted into breast milk in a clinically non-significant amount even after oral administration.

Because a low dose used and a poor absorption into the plasma of most dermatological preparations for topical use, its appearance in the breast milk is even less likely.

The American Academy of Pediatrics rated it as usual compatible with breastfeeding.


We do not have alternatives for Flufenamic Acid since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.


Flufenamic Acid belongs to this group or family:


Main tradenames from several countries containing Flufenamic Acid in its composition:


Variable Value Unit
Molecular weight 281 daltons


  1. Köhler G, Tressel W, Dell HD, Doersing M, Fischer W, Kamp R, Langer M, Richter B, Wirzbach E. [Plasma- and tissue concentrations following intramuscular administration of etofenamat. Pharmacokinetics of etofenamat and flufenamic acid in plasma, synovium, and tissues of patients with chronic polyarthritis after administration of an oily solution of etofenamat]. Arzneimittelforschung. 1992 Abstract
  2. Lentjes EG, van Ginneken CA. Pharmacokinetics of flufenamic acid in man. Int J Clin Pharmacol Ther Toxicol. 1987 Abstract
  3. Buchanan RA, Eaton CJ, Koeff ST, Kinkel AW. The breast milk excretion on flufenamic acid. Curr Ther Res Clin Exp. 1969 Abstract

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