Last update: May 22, 2019
Safe. Compatible.
Not risky for breastfeeding or infant.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
Bromhexine is also known as
Bromhexine in other languages or writings:
Main tradenames from several countries containing Bromhexine in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 20 - 25 | % |
Molecular weight | 413 | daltons |
Protein Binding | 95 - 99 | % |
pKa | 9,3 - 19,9 | - |
Tmax | 1 | hours |
T1/2 | 7 - 15 | hours |
Write to us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Bromhexine is metabolized into Ambroxol (Schaefer 2007 p72).
Effectiveness of this drug has not been established (Prescrire 2017, INSALUD 2001).
Oral administration two to three times a day.
At latest update, relevant published data on excretion into breast milk were not found.
Because of high serum protein-binding capacity (AEMPS 2016), excretion into breast milk in significant amount is seemingly unlikely.
Its low oral bioavailability (AEMPS 2016)causes a poor absorption into infant's serum as from breast milk, except in prematures and in the early neonatal period in which intestinal absorption may be increased.
Known adverse reactions are rare and mild.
Secretion of Prolactin and other hormones have not been affected by taking this medication (Tuimala 1981).
Autores expertos lo consideran seguro durante la lactancia (Schaefer 2007 p644).
See below the information of this related product: