Last update: Aug. 19, 2012

Brinzolamide

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

It is a carbonic anhydrase (CA) inhibitor sulphonamide drug which is used as 1% drops for topical treatment to lower intraocular pressure or glaucoma. EMEA and FDA have informed of very low serum levels found to be bound to CA red blood cells even after oral ingestion. For this reason and because it is usually used as a topical treatment its presence in mother’s milk is unlikely.

Like most ophthalmologic compounds for topical use, a low dose and poor absorption make it compatible with breastfeeding. Pressing conjunctiva sack for a couple of minutes to lessen systemic absorption.

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

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Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Group

Brinzolamide belongs to this group or family:

Tradenames

Main tradenames from several countries containing Brinzolamide in its composition:

Pharmacokinetics

Variable Value Unit
Molecular weight 384 daltons
Protein Binding 63 %
Tmax 2 hours
T1/2 4032 hours

References

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