Last update: Jan. 16, 2021

A10BB12

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Sulfonylurea that stimulates endogenous insulin secretion. May cause hypoglycemia.
Indicated in the treatment of type 2 diabetes.
Oral administration, one daily dose

We did not find published data regarding the excretion of this substance through breast milk at the time this last update was completed.

The manufacturer (AEMPS 2o18, Sanofi 2016) and some authors do not consider it safe in lactation based on a publication of excessive passage to milk in animals (Hale, Serrano 2015)

Until there is further published data on this drug in relation to breastfeeding, known safer alternatives may be preferable, especially during the neonatal period and in cases of prematurity.

Diet, exercise, and breastfeeding improve blood sugar levels.


See below the information of this related product:

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

A10BB12 is Glimepiride in ATC Code/s.

Is written in other languages:

Tradenames

Main tradenames from several countries containing A10BB12 in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 490 daltons
Protein Binding 100 %
VD 0,12 l/Kg
pKa 4,32 -
Tmax 2 - 3 hours
T1/2 5 - 9 hours

References

  1. AEMPS. Glimepirida. Ficha técnica. 2018 Full text (in our servers)
  2. Sanofi-Aventis. Glimepiride. Drug Summary. 2016 Full text (in our servers)
  3. Serrano Aguayo P, García de Quirós Muñoz JM, Bretón Lesmes I, Cózar León MV. Tratamiento de enfermedades endocrinológicas durante la lactancia. [Endocrinologic diseases management during breastfeeding.] Med Clin (Barc). 2015 Jan 20;144(2):73-9. Abstract

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