Last update: May 16, 2019
Very unsafe. Contraindicated.
Use of an alternative or cessation of breastfeeding.
A centrally-acting and indirect sympathomimetic appetite suppressant similar to dexamfetamine which can create dependency (WHO 2003).
It has been used in the treatment of obese people.
It produces insomnia, anorexia, nervousness and major side effects, especially cardiac effects (Cheung 2013). There have been reports of psychosis and hallucinations and a case of ketoacidosis in a woman affected by diabetes (Branis 2015).
Although there is no published data on its effects on breastfed infants, according to the manufacturer it is excreted in breastmilk, meaning its use during breastfeeding is not recommended (UDS 2011).
The lack of published pharmacological data makes it difficult to accurately predict its possible excretion in breastmilk.
Until there is more published data on this drug in relation to breastfeeding, safer known alternatives are preferable, especially during the neonatal period and in case of prematurity.
There is a risk it may become a drug of abuse (WHO 2003) and was withdrawn from sale in the European Union in 2000 (AEMPS 2000).
None of the current pharmacological treatments for obesity is safe for use in pregnant or breastfeeding women (Rodríguez 2016).
There is good quality evidence that exclusive breastfeeding helps to regain pre-pregnancy weight earlier than if breastfeeding is partial (mixed) or there is no breastfeeding, and that prolonged breastfeeding helps maintain that loss and as well as body fat loss (Schalla 2017, López 2016, Neville 2014, Sámano 2013, Hatsu 2008, Dewey 2004, 2001 and 1993, Kramer 1993).
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Instituto de Salud Infantil, Grecia-Institute of Child's Health in Greece
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM