Last update July 16, 2023
Compatible
We do not have alternatives for Varicella-zoster immunoglobulin since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
Varicella-zoster immunoglobulin belongs to this group or family:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 0 | % |
Molecular weight | 160.000 | daltons |
Tmax | 3 | hours |
T½ | 432 - 720 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by La Liga de la Leche, España of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Human varicella-zoster immune globulin is an antibody solution obtained from the plasma of selected donors who have antibodies to human herpesvirus 3 (varicella-zoster virus 1). It is used for postexposure prophylaxis of varicella infections in high-risk populations, as well as to reduce the severity of infections.
Its very high molecular weight makes it very unlikely to pass into breast milk in clinically significant quantities.
Due to its protein nature, it is inactivated in the gastrointestinal tract and is not absorbed (oral bioavailability practically nil), which makes it difficult or impossible for it to pass into the infant's plasma from ingested breast milk, except in premature infants and in the immediate neonatal period, where there may be greater intestinal permeability.
It can be administered intramuscularly to infants weighing less than 2 kg.
Expert authors consider the use of this medication safe during breastfeeding. (LactMed, Briggs 2015)
See below the information of this related product: