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Polypeptide with antibiotic properties isolated from the fermentation of Bacillus brevis. Contains a mixture of gramicidin and thyrocidine. Used topically in skin and mouth infections, often in association with benzocaine.
At the date of the last update, we found no published data on its excretion in breast milk.
As it is not water soluble, it is not absorbed through the skin. It is not used systemically as it is very toxic (renal and hepatic). May cause contact dermatitis. (Goldman 1948)
Given its systemic absorption by oral route which is practically nil and its high molecular weight, it is highly unlikely to pass into breast milk. Do not apply to the breast to prevent ingestion by the infant.
It has been withdrawn from the market in some countries due to its lack of therapeutic efficacy. (WHO 2005)
See below the information of this related product: