Last update Aug. 31, 2022
Compatible
We do not have alternatives for Цефиксим since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Main tradenames from several countries containing Цефиксим in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 30 - 50 | % |
Molecular weight | 508 | daltons |
Protein Binding | 65 - 70 | % |
VD | 0.1 | l/Kg |
Tmax | 2 - 6 | hours |
T½ | 3 - 4 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by IHAN of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
This is a third generation Cephalosporin. Oral administration.
At latest update relevant data on excretion into breast milk were not found.
All Cephalosporins for which there is available information are excreted in breast milk in an amount that is therapeutically non-significant. (Rowe 2013)
Cephalosporins are widely used in Pediatrics, even from the neonatal period (Lignieres 201, Hamilton 2020), with very good tolerance, so it is very unlikely that, in small amounts through milk, they can cause problems in infants.
Although rare, the possibility of transient gastroenteritis due to alteration of the intestinal flora in infants whose mothers take antibiotics should be taken into account. (Ito 1993)
Expert authors consider the use of this medication to be compatible or probably compatible during breastfeeding. (Hale, LactMed, Briggs 2015, Bar-Oz 2003, Fulton 1992)