Last update Sept. 3, 2022
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Trimethobenzamide Hydrochloride in other languages or writings:
Trimethobenzamide Hydrochloride belongs to these groups or families:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | Alta - Hig | % |
pKa | 14.68 | - |
Tmax | 0.5 - 0.75 | hours |
T½ | 7 - 9 | hours |
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e-lactancia is a resource recommended by IHAN of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a sedative antihistamine, derived from monoethanolamine, which is used as an antiemetic in the control of nausea and vomiting. Intramuscular administration 3 to 4 times a day.
At the date of the last update we did not find any published data on its excretion in breast milk.
The scarcity of known pharmacokinetic data does not allow to predict the magnitude of its possible excretion in breast milk.
It is a drug with very few bibliographical references and marketed in few countries.
Some authors consider it a drug probably compatible with lactation. (Briggs 2015, Mahadevan 2006)
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable, especially during the neonatal period and in the event of prematurity.