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It is a monoclonal antibody directed against interleukin-13 that is used in the treatment of moderate to severe atopic dermatitis. Weekly subcutaneous administration.
At the date of the last update we did not find any published data on its excretion in breast milk.
It´s very high molecular weight (> 100,000 Da) makes it very unlikely to pass into breast milk in a significant quantity, since molecules of more than 800 - 1,000 Da do not pass into breast milk.
Due to its protein nature, it is inactivated in the gastrointestinal tract without being absorbed (practically nil oral bioavailability) and this hinders or prevents its passage into the infant´s plasma from ingested breast milk, except for premature infants and during the immediate neonatal period when there might be a greater intestinal permeability.