Last update Nov. 25, 2019
Very Low Risk
Aminoglycoside antibacterial with actions and uses similar to those of gentamicin.
Administration by intramuscular or intravenous injection, or by inhalation
Excreted into breast milk in non-significant amount (Takase 1975, Uwaydah 1975, Festini 2006) without harm effects observed among breastfed infants of mothers treated with Tobramycin (Festini 2006 y 2004, Bourget 1993).
In addition, a low oral bioavailability renders concentration in the infant's plasma be nil or low.
Be aware of the risk of acute diarrhea by alteration of normal gut flora.
Several experts consider the use of this medication safe during breastfeeding (Hale 2019, Briggs 2017, Rowe 2013, Schaefer 2007, Chin 2001, Niebyl 1992).
When used in eye drops, because of a low dose and topical application with minimal absorption in the serum, it is compatible while breastfeeding.
We do not have alternatives for Tobramycin since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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