Last update Aug. 23, 2021
Likely Compatibility
We do not have alternatives for Tirofiban Hydrochloride.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Tirofiban Hydrochloride in other languages or writings:
Tirofiban Hydrochloride belongs to this group or family:
Main tradenames from several countries containing Tirofiban Hydrochloride in its composition:
Variable | Value | Unit |
---|---|---|
Molecular weight | 495 | daltons |
Protein Binding | 65 | % |
VD | 0.3 -0.6 | l/Kg |
pKa | 3.17 | - |
T½ | 1.4 - 2.2 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a non-peptide antagonist of the platelet surface receptor GP IIb/IIIa, preventing its binding with fibrinogen and blocking platelet aggregation.
Indicated in the prevention of myocardial infarction in acute coronary syndromes and in early percutaneous coronary intervention (PCI).
Administration by intravenous infusion for a maximum of 4-5 days.
At the date of the last update, there was no available published data on its excretion in breast milk.
Its pharmacokinetic data (large volume of distribution, moderately high molecular weight and short half-life) make it unlikely that it will pass into breast milk in a clinically significant quantity.
The risk can be minimized by waiting to breastfeed again between 6 and 8 hours after the last administration of the medicine.
The limitation to breastfeed will depend on the clinical situation of the mother.