Last update May 16, 2019
Very Low Risk
We do not have alternatives for Technetium 99m Medronate (MDP) since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Technetium 99m Medronate (MDP) is also known as
Technetium 99m Medronate (MDP) in other languages or writings:
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e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
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The metastable Technetium 99 (99mTc) is a radioactive isotope that emits gamma radiation. Its half-life of radioactive decay is 6.0 hours
After radioactive labelling with sodium pertechnetate (99mTc) solution, the technetium (99mTc) medronate solution obtained is used in bone scintigraphy.
Between 0.01% (MDP blocked, with a T ½ of 5.2 hours) and 0.03% (MDP non-blocked, with a T ½ of 3.6 hours) of the administered dose is excreted in breast milk (Leide 2016, Liepe 2016).
Breastfeeding interruption periods or avoiding close contact are calculated so that the infant is not exposed to more than 1 millisievert (1 mSv = 0.1 rem) of radiation (ARSAC 2019, US.NCR 2016, ICRP 2008, Stabin 2000 ).
An adult receives between 5 and 10 mSv annually from environmental radiation.
The main regulatory agencies which manage radioactive substances and experts consider that breastfeeding can be resumed immediately after a diagnostic test with Tc 99m medronate (ARSAC 2019 p51, USNRC 2016 Tabl U.3, ICRP 2008 p163, Stabin 2000).
Some agencies (ARSAC 2019, ICRP 2008) consider it more prudent to discontinue breastfeeding for about 4 hours, expressing breast milk once and instead offering milk previously expressed and stored in a refrigerator prior to testing.
Milk expressed after the scintigraphy can be frozen and used after 10 radioactive half lives: 10 x 6.0 = 60 hours = 3 days (Hale 2017 p2019).
t is not necessary to avoid close contact with the infant (Mountford 1999).
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