Last update Oct. 24, 2024

Suramine Sodium

Limited compatibility

Unsafe. Moderate/severe adverse effects. Compatible under certain circumstances. Follow-up recommended. Use safer alternative or discontinue breastfeeding from 5 to 7 T ½ . Read Commentary.

Suramin is a trypanocide used in the treatment of African trypanosomiasis (sleeping sickness) and as an anthelmintic in the treatment of onchocerciasis. Intravenous administration.

At the date of the last update we found no published data on its excretion in breast milk.

Its high molecular weight and high binding to plasma proteins make its passage into breast milk improbable, but its very long half-life would facilitate it.

Its low oral bioavailability makes it difficult to pass into the infant's plasma from ingested breast milk, except in premature infants and in the immediate neonatal period when intestinal permeability may be higher.

The precarious clinical situation of affected mothers, which may prevent them from breastfeeding, must be taken into account.

Alternatives

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Suramine Sodium is also known as


Suramine Sodium in other languages or writings:

Group

Suramine Sodium belongs to this group or family:

Tradenames

Main tradenames from several countries containing Suramine Sodium in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. baja / poor %
Molecular weight 1429 daltons
Protein Binding 99.7 %
864 - 1440 hours

References

  1. Pérez JL, Carranza C, Mateos F. Antiparasitarios. Revisión de los fármacos útiles en el tratamiento de parasitosis clásicas y emergentes. \ [Antiparasitic drugs. Review of the useful drugs in the treatment of classic and emergent parasitic diseases]. Rev Esp Quimioter. 2009 Jun;22(2):93-105. Review. Spanish. Abstract Full text (link to original source) Full text (in our servers)
  2. WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Abstract Full text (link to original source) Full text (in our servers)

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