Last update Jan. 29, 2022
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Sulfadiazine; Sulphadiazine is also known as
Sulfadiazine; Sulphadiazine in other languages or writings:
Sulfadiazine; Sulphadiazine belongs to these groups or families:
Main tradenames from several countries containing Sulfadiazine; Sulphadiazine in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 85 | % |
Molecular weight | 250 | daltons |
Protein Binding | 55 | % |
pKa | 6.99 | - |
Tmax | 3 - 6 | hours |
T½ | 10 (7 - 17) | hours |
M/P ratio | 1 | - |
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e-lactancia is a resource recommended by IHAN of Spain
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It is a short-acting sulfonamide with uses similar to sulfamethoxazole. Together with pyrimethamine it is used in the treatment of toxoplasmosis. Oral administration every 4 - 6 hours.
Since the last update we have not found published data on its excretion in breastmilk.
Sulphamides are excreted in small amounts in breast milk: 6 to 94 micrograms/ml, 1.6% of the total dose. (Briggs 2015)
Reports of adverse effects are rare (Briggs 2015). Avoid in suspected glucose-6-phosphate dehydrogenase deficiency.
Due to the greater toxicity than that of other antimicrobials and their high acquired resistance, the use of sulfonamides is currently very scarce. (Pérez 2003)