Last update Aug. 20, 2022

スガマデクスナトリウム

Compatible

Safe substance and/or breastfeeding is the best option.

It is a modified gamma-cyclodextrin that binds to rocuronium or vecuronium, reversing its neuromuscular blocking action. Used intravenously.

Since the last update we have not found published data on its excretion in breast milk.

Its high molecular weight makes it unlikely that it will pass into milk in significant amounts.

Its low oral bioavailability would make it difficult its passage to the infant’s plasma through breast milk. (EMA 2017)

Side effects are rare and mild. It is administered in single or isolated doses.
 

Sugammadex can be used during breastfeeding. (LactMed, EMA 2017)

Alternatives

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

スガマデクスナトリウム is Sugammadex Sodium in Japanese.

Is written in other languages:

Group

スガマデクスナトリウム belongs to this group or family:

Tradenames

Main tradenames from several countries containing スガマデクスナトリウム in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. ≈ 0 %
Molecular weight 2.178 daltons
Protein Binding 0 %
VD 0.2 l/Kg
pKa 2.82 -
2 hours

References

  1. Reece-Stremtan Sarah, Campos Matilde, Kokajko Lauren, and The Academy of Breastfeeding Medicine. Breastfeeding Medicine. ABM Clinical Protocol #15: Analgesia and Anesthesia for the Breastfeeding Mother, Revised 2017. Breastfeed Med. 2017 Nov;12(9):500-506. Full text (link to original source) Full text (in our servers)
  2. EMA. Sugammadex. Ficha técnica. 2017 Full text (in our servers)
  3. EMA. Sugammadex. Drug Summary. 2017 Full text (in our servers)

Total visits

1,644

Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write us at elactancia.org@gmail.com

e-lactancia is a resource recommended by El Parto Es Nuestro of Spain

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM