Last update Jan. 4, 2023

Succimer (DMSA)

Low Risk

Possibly safe. Probably compatible. Mild risk possible. Follow up recommended. Read the Comment.

Succimer is a heavy metal chelating agent containing dimercaptosuccinic acid (DMSA). It is used to treat intoxication with lead (also mercury and arsenic). Succimer, labeled with a radionuclide such as technetium-99m, is also used in nuclear medicine.

At the date of the last update we did not find any published data on its excretion in breast milk.

The paucity of known pharmacokinetic data does not allow prediction of the amount of its possible excretion in breast milk.

Lead having been chelated by DMSA is eliminated through the urine and although it is unlikely to be secreted into breast milk, it would be prudent to pump-out and dispose expressed milk for the next 5 days, until lead levels have lowered. (Hale)

Alternatives

We do not have alternatives for Succimer (DMSA).

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Succimer (DMSA) is also known as


Succimer (DMSA) in other languages or writings:

Tradenames

Main tradenames from several countries containing Succimer (DMSA) in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 182 daltons
pKa 3.37 -
Tmax 1 - 2 hours
48 hours

References

  1. Schwarz Ph. Succimer. Drug Summary. 2007 Full text (in our servers)

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