Last update Oct. 31, 2018

Strychnos spireana

Very High Risk

Very unsafe. Contraindicated. Use of an alternative or cessation of breastfeeding. Read the Comment.

The dried seed of the Strychnos nux-vomica plant of the Loganiaceae family is used. It contains brucine and strychnine.
Traditionally used without scientific evidence to treat various digestive and cardiovascular disorders, depression, migraine and asthenia (Ma 2015, Palombo 2006, Blumenthal 1998, p355).

Since the last update we have not found published data on its excretion in breastmilk.

Highly toxic (neuroconvulsant) and easily lethal (Ma 2015, Mehta 2015, CDC-NIOSH 2005, Blumenthal 1998 p355).

It is not approved by Commission E of the German Federal Institute for Drugs and Medical Devices (Blumenthal 1998 p355).

This plant is on the list of plants whose sale to the public is prohibited in Spain due to its toxicity (MSC 2004). Strychnine is considered very toxic by several health agencies (CDC-NIOSH 2005, INSHT 2000).


We do not have alternatives for Strychnos spireana.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Strychnos spireana is Nux Vomica in Latin, another name.

Is written in other languages:

Strychnos spireana is also known as


Strychnos spireana belongs to this group or family:


Main tradenames from several countries containing Strychnos spireana in its composition:

  • Fenokomp 39™. Contains other elements than Strychnos spireana in its composition


  1. Guo R, Wang T, Zhou G, Xu M, Yu X, Zhang X, Sui F, Li C, Tang L, Wang Z. Botany, Phytochemistry, Pharmacology and Toxicity of Strychnos nux-vomica L.: A Review. Am J Chin Med. 2018 Abstract
  2. Ma L, Gu R, Tang L, Chen ZE, Di R, Long C. Important poisonous plants in tibetan ethnomedicine. Toxins (Basel). 2015 Abstract
  3. Mehta P, Shah R, Lohidasan S, Mahadik KR. Pharmacokinetic profile of phytoconstituent(s) isolated from medicinal plants-A comprehensive review. J Tradit Complement Med. 2015 Abstract
  4. Palombo EA. Phytochemicals from traditional medicinal plants used in the treatment of diarrhoea: modes of action and effects on intestinal function. Phytother Res. 2006 Abstract
  5. CDC-NIOSH. Strychnine. International Chemical Safety Cards (ICSC). 2005 Full text (in our servers)
  6. MSC - Ministerio de Sanidad y Consumo de España. ORDEN SCO/190/2004, de 28 de enero, por la que se establece la lista de plantas cuya venta al público queda prohibida o restringida por razón de su toxicidad. BOE 2004; 32:5061-6065 Full text (link to original source) Full text (in our servers)
  7. INSHT - Instituto Nacional de Seguridad e Higiene en el Trabajo- Estricnina. Fichas Internacionales de Seguridad Química (FISQ). 2000 Full text (in our servers)
  8. Blumenthal M, Busse WR, Goldberg A, Gruenwald J, Hall T, Riggins CW, Rister RS, editors. The American Botanical Council. The Complete German Commission E Monographs. Therapeutic Guide to Herbal Medicines. 1st ed. Integrative Medicine Com; Boston, MA, USA: 1998

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