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Sheehan's syndrome or hypopituitarism is caused by severe postpartum hemorrhage with maternal shock resulting in hypoperfusion, necrosis and thrombotic infarction of the pituitary. Hypopituitarism can also occur after severe trauma and after surgery for pituitary masses. Secretion of all pituitary hormones, including prolactin, is absent or deficient. Breast involution occurs, lactation fails and menstruation does not resume. It may occur in 1 or 2 in 10,000 deliveries. (Lawrence 2016 p577)
Depending on the degree of destruction of the gland lactation may be possible. (Pineyro 2022, Aulinas 2022)
Cases of successful lactation with hypopituitarism have been described based on maternal desire, daily nasal spray oxytocin administration, and frequent milk expression. In one case the mother initiated milk production at 2 weeks and was able to breastfeed her infant one year. (Lawrence 2016 p677).
Note: we speak here of high risk, not because there is a risk for the mother or the baby, but because it is difficult to achieve lactation in the absence of prolactin.