Last update Aug. 17, 2019
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Rizatriptan Benzoate in other languages or writings:
Main tradenames from several countries containing Rizatriptan Benzoate in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 40 - 45 | % |
Molecular weight | 392 | daltons |
Protein Binding | 14 | % |
VD | 1.8 | l/Kg |
pKa | 9.56 | - |
Tmax | 1 - 2.5 | hours |
T½ | 1.6 - 3 | hours |
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e-lactancia is a resource recommended by IHAN of Spain
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Selective agonist for the vascular receptor of 5-hydroxytryptamine-1 (5-HT1, serotonin) with vasoconstrictor action at the intracranial level.
Indicated in acute migraine attack.
Oral administration in a daily dose.
Since the last update we have not found published data on its excretion in breastmilk.
Several expert authors consider its use to be safe or probably safe during breastfeeding (Hale 2019, Briggs 2017, Amundsen 2015, Duong 2010).
Its use, usually in isolated doses, makes the occurrence of adverse effects in infants unlikely (Jürgens 2009).
As there is less published data than for other drugs in the same group, safer known alternatives may be preferable, especially during the neonatal period and in cases of prematurity.