Last update Aug. 18, 2021
Very Low Risk
Synthetic derivative of nicotinamide indicated in the treatment of tuberculosis.
Oral administration in a daily or three weekly doses.
Authorized use in pediatrics from one month of age.
It is excreted in breast milk in a clinically non-significant amount (Holdiness 1984).
No problems have been observed in infants whose mothers took it (Drobac 2005).
Various medical societies and expert consensus consider the use of this medication safe during breastfeeding (Baquero 2015, ATC 2003, CDC 2003).
WHO Essential Medicines List: compatible with breastfeeding (WHO 2002).
We do not have alternatives for Pyrazinamide (PZA) since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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