Last update Aug. 17, 2019
Compatible
We do not have alternatives for プロテアーゼ since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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プロテアーゼ is Proteases in Japanese.
Is written in other languages:プロテアーゼ is also known as
Main tradenames from several countries containing プロテアーゼ in its composition:
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Enzymes which are able to hydrolyze proteins.
They are found in all living beings and are an important part of digestive enzymes: pancreatic (trypsin and chymotrypsin) and gastric (pepsin)..
They are orally used for gastrointestinal disorders and topically on wounds and burns. Some (chymotrypsin) are used in cataract surgery.
There is an increasing trend on type and therapeutic uses (Craik 2011). There is no evidence of its efficacy in the treatment of post-traumatic or post-surgical inflammations or in respiratory diseases.
At latest update relevant published data on excretion into breast milk were not found.
Because the small dose used and low plasma uptake of most topical dermatological and ophthalmological preparations it is unlikely that significant amounts of it will pass into breastmilk.
Its high molecular weight turns further improbable any excretion into breastmilk.
Due to its protein nature, when orally taken it is digested by the infant’s intestine, hence its absorption and passage to plasma should be nil.
The manufacturer considers it compatible with breastfeeding (AEMPS 2016).
Few studies with low levels of evidence on oral use of proteases to alleviate breast congestion have shown uneven results (ABM 2016, Mangesi 2016).