Last update July 1, 2015

プロピトカイン

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Anesthetic drugs for topical use both dermatological and odontological have almost nil absorption when properly used. Do not apply on the breast. Otherwise, do it after having nursed and cleanse it thoroughly with water before next feeding.

Alternatives

  • Lidocaine ( Safe. Compatible. Minimal risk for breastfeeding and infant.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.
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Other names

プロピトカイン is Prilocaine in Japanese.

Is written in other languages:

Group

プロピトカイン belongs to this group or family:

Tradenames

Main tradenames from several countries containing プロピトカイン in its composition:

List of 28 tradenames
  • Anesderm™. Contains other elements than プロピトカイン in its composition
  • Asthesia™. Contains other elements than プロピトカイン in its composition
  • Citanest™
  • Citanest Octapressine™
  • Citocaina™
  • Dolones™. Contains other elements than プロピトカイン in its composition
  • Emla™. Contains other elements than プロピトカイン in its composition
  • Emlap™. Contains other elements than プロピトカイン in its composition
  • Emlapatch™. Contains other elements than プロピトカイン in its composition
  • Emlocaine™. Contains other elements than プロピトカイン in its composition
  • Estesia™. Contains other elements than プロピトカイン in its composition
  • Eutecaina™. Contains other elements than プロピトカイン in its composition
  • Funis™. Contains other elements than プロピトカイン in its composition
  • Lidiprine™. Contains other elements than プロピトカイン in its composition
  • Liprikaine™. Contains other elements than プロピトカイン in its composition
  • Lipro™. Contains other elements than プロピトカイン in its composition
  • Medicaina™. Contains other elements than プロピトカイン in its composition
  • Opralix™. Contains other elements than プロピトカイン in its composition
  • Oraqix™. Contains other elements than プロピトカイン in its composition
  • Prilotekal™
  • Prinex™. Contains other elements than プロピトカイン in its composition
  • Pristesin F™
  • Takipril™
  • Tapin™. Contains other elements than プロピトカイン in its composition
  • Topla™. Contains other elements than プロピトカイン in its composition
  • Topsy™. Contains other elements than プロピトカイン in its composition
  • Xylocream™. Contains other elements than プロピトカイン in its composition
  • Xylonest™

Pharmacokinetics

Variable Value Unit
Molecular weight 220 daltons
Protein Binding 55 %
VD 2.6 l/Kg
Tmax (Derm): 4 - 10 hours
T½ 1.2 hours

References

  1. PDR.net. EMLA. Drug Summary. 2014 Full text (in our servers)
  2. Touma S, Jackson JB. Lidocaine and prilocaine toxicity in a patient receiving treatment for mollusca contagiosa. J Am Acad Dermatol. 2001 Abstract
  3. Essink-Tebbes CM, Wuis EW, Liem KD, van Dongen RT, Hekster YA. Safety of lidocaine-prilocaine cream application four times a day in premature neonates: a pilot study. Eur J Pediatr. 1999 Abstract
  4. Vickers ER, Marzbani N, Gerzina TM, McLean C, Punnia-Moorthy A, Mather L. Pharmacokinetics of EMLA cream 5% application to oral mucosa. Anesth Prog. 1997 Abstract
  5. Brackbill Y, Kane J, Manniello RL, Abramson D. Obstetric premedication and infant outcome. Am J Obstet Gynecol. 1974 Abstract

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e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain

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