Last update Oct. 14, 2022
Very Low Risk
Ureidopenicillin with a similar use to ticarcillin. Indicated in the treatment of infections caused by Pseudomonas aeruginosa, and by other susceptible bacteria. Intravenous administration.
It is excreted into breastmilk in a clinically insignificant amount. (Wyeth 2007, Baier 1982 (in LacMed), Chaplin 1982 (in Hale))
Because it lacks of oral bioavailability, seems difficult any pass to the infant’s plasma through the breast milk ingested, except on premature infants and immediate neonatal period, in which there may be an increased intestinal permeability.
Authorized use in infants and small infants. (Chen 2009)
Although rare, the possibility of transient gastroenteritis due to alteration of the intestinal flora in infants whose mothers take antibiotics should be taken into account. (Ito 1993).
Expert authors consider the use of this medication to be safe during breastfeeding. (Hale, LacMed, Briggs 2015)
We do not have alternatives for Piperacillin Sodium since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM